Renal-cell carcinoma – novel concepts of classification

Review Article, Pol J Public Health 2019;129(2): 61-63

Maria Pyda-Karwicka1,2, Malwina Karwicka1, Magdalena Orłowska3,
Mariusz Krata4, Agnieszka Pedrycz5

1 1 School of Medicine Jan Kochanowski University in Kielce, Poland
2 Holy Cross Cancer Center Kielce, Poland
3 International Institute of Molecular and Cell Biology in Warsaw, Poland
4 Internal Medicine Ward, Independent Public Healthcare Centre Szczebrzeszyn, Poland
5 Chair and Department of Histology and Embryology with Experimental Cytology Unit, Medical University in Lublin, Poland

DOI_disc_logo 10.2478/pjph-2019-0014

© 2019 Medical University of Lublin. This is an open access article distributed under the Creative Commons Attribution-NonComercial-No Derivs licence (


Renal cancer, according to the Polish National Cancer Registry, was the cause of 4% of cancer cases in men and 3% of cases in women in 2010. Most often it affects men over 65, although it may also concern infants. In 2010, the number of reported cases for men was 2,700 and 1,900 for women. For the last three decades – up to 1990, the incidence of kidney cancer has increased significantly. Currently, it remains at the stable level of morbidity. One of the most significant issues of modern diagnostics and treatment of renal cancer is the problem of its heterogeneity brin-ging many difficulties in systematization and categorization of this neoplasm. The World Health Organization Classification of Renal Tumors has been published in 2004 and is currently sup­plemented with new classification units, which, according to ISUP (International Society of Urological Pathology), should be considered as separate groups of kidney epithelial cancers.

Keywords: renal cell carcinoma, novel cancer classification, PRCC characteristic.

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