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Zdrowie Publiczne - Polish Journal of Public Health
Polish Journal of Public Health
Medical University Publishing House of Lublin
20-093 Lublin ul. Chodźki 1 Poland
tel/fax: +48 81 742 37 62
ISSN: PL 0044-2011
Medical University of Lublin

Former journal 'Zdrowie' founded in 1885 by Józef Polak M.D.  

Zdrowie Publiczne 2009 119(2);223-227 Review Article

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Cancer chemoprevention – application perspectives in prophylactics and therapy

Cyranka Małgorzata, Kapka Lucyna, Rzeski Wojciech

Summary

Cancer chemoprevention is defi ned as the use of natural,synthetic, or biological and chemical agents to reverse, suppress,or prevent either the initial phase of carcinogenesis or the progression to invasive cancer in high-risk populations.Several chemopreventive agents (including tamoxifen) are proved to be effective in preventing the development of cancer, while several remain just as dietary restrictions. Chemopreventive agents have been reported to interfere with a specifi c stage of the carcinogenesis and different mechanisms involved in anticancer activity have been described.
This article summarises agents that have a chemopreventive potential against cancer, as well as these ones which are already in clinical use against cancer. This review will also highlight current clinical research in hemoprevention.

Słowa kluczowe: carcinogenesis, chemoprevention, chemoprewencja, kancerogenezy

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